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Paeoniflorin Chemical Pharmaceutical Raw Materials brown powder With Hypoglycemic Effect , 23180-57-6

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Paeoniflorin Chemical Pharmaceutical Raw Materials brown powder With Hypoglycemic Effect , 23180-57-6

China Paeoniflorin Chemical Pharmaceutical Raw Materials brown powder With Hypoglycemic Effect , 23180-57-6 supplier
Paeoniflorin Chemical Pharmaceutical Raw Materials brown powder With Hypoglycemic Effect , 23180-57-6 supplier Paeoniflorin Chemical Pharmaceutical Raw Materials brown powder With Hypoglycemic Effect , 23180-57-6 supplier Paeoniflorin Chemical Pharmaceutical Raw Materials brown powder With Hypoglycemic Effect , 23180-57-6 supplier Paeoniflorin Chemical Pharmaceutical Raw Materials brown powder With Hypoglycemic Effect , 23180-57-6 supplier

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Product Details:

Place of Origin: China
Brand Name: LSW
Certification: ISO9001, SGS, USP, BP
Model Number: 23180-57-6

Payment & Shipping Terms:

Minimum Order Quantity: 10g
Price: Negotiated (Best offer will be provided based on your quantity)
Packaging Details: Professional discreet package, Foil bag or as your demand.
Delivery Time: Within 24 hours after payment
Payment Terms: Western Union, MoneyGram, Bank transfer, Bitcoin
Supply Ability: Plenty In Stock (New Batch)
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Detailed Product Description
Molecular Formula: C23H28O11 Molecular Weight: 480.45
CAS No.: 23180-57-6 Specifications: 10% 20% 50% 95% 98%
Appearance: Light Brown Yellow Powder Melting Point: 196 ℃
Email: Coco@yuanchengtech.com Whatsapp: +86 18872220806

 

Chemical Compound Powder Paeoniflorin With Hypoglycemic Effect 23180-57-6

 

 

Wuhan Lianshangwang Technology Co.,LTD

Contact person:helena liu

coco@yuanchengtech.com

whatsapp:+86 18872220806

 

 

 

Paeoniflorin Details:

 

Alias Paeonia moutan
Molecular formula C23H28O11
Molecular weight 480.45
CAS No. 23180-57-6
Specifications 10% 20% 50% 95% 98%
Appearance light brown yellow powder
Melting point 196 ℃
Solubility soluble in water, methanol, soluble in ethanol
extract Part root
Plant sources
Paeonia lactifloraPall.
Extract solvent Soluble in water and ethanol
Usage antiinflammatory, antispasmodic, antihypertensive, antidiuretic
Storage Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.

Approach

 

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Chemical structure

 

Chemical Structure

 

 

Paeoniflorin Application


Paeoniflorin is a herbal constituent extracted from the root of Paeonia albiflora Pall. Paeoniflorin has broad pharmacological effects, such as analgesic, anti-diuretic,anti-inflammatory,anti-convulsant, vasodilatic, and etc. In a study, paeoniflorin effe.

 

Paeoniflorin Chemical Pharmaceutical Raw Materials brown powder With Hypoglycemic Effect , 23180-57-6

 

 

 

Paeoniflorin Effects

 

Herbal constituent of peony root. It is used in Chinese traditional medicine for its spasmolytic and pain-relieving properties. Exhibits anticoagulant, neuromuscular blocking, cognition-enhancing, immunoregulating, and antihyperglycemic effects.
Clinical application :1, 2 anti~inflammatory effects, analgesic 3, from regulation 4, widely used to treat rheumatoid arthritis, coronary heart disease, gynecological disease

 

 

 

Paeoniflorin Description:

 

(1) Paeoniflorin is a chemical compound which is one of the major constituents of an herbal medicine derived from Paeonia lactiflora. It can also be isolated from the fresh water fern Salvinia molesta. In Paeonia, it can form new compounds with addition of phenolic substituents. In a study in female rats, paeoniflorin was found to inhibit the production of testosterone within the ovaries by promoting the activity of aromatase.

 

(2) Heat shock proteinsare induced by various physical, chemical, and biological stresses. HSPs are known to function as molecular chaperones, and they not only regulate various processes of protein biogenesis but also function as lifeguards against proteotoxic stresses. Because it is very useful to discover nontoxic chaperone-inducing compounds, we searched for them in herbal medicines. Some herbal medicines had positive effects on the induction of HSPs (Hsp70, Hsp40, and Hsp27) in cultured mammalian cells. We next examined 2 major constituents of these herbal medicines, glycyrrhizin and paeoniflorin, with previously defined chemical structures. Glycyrrhizin had an enhancing effect on the HSP induction by heat shock but could not induce HSPs by itself. In contrast, paeoniflorin had not only an enhancing effect but also an inducing effect by itself on HSP expression.

Thus, paeoniflorin might be termed a chaperone inducer and glycyrrhizin a chaperone coinducer. Treatment of cells with paeoniflorin but not glycyrrhizin resulted in enhanced phosphorylation and acquisition of the deoxyribonucleic acid-binding ability of heat shock transcription factor 1, as well as the formation of characteristic HSF1 granules in the nucleus, suggesting that the induction of HSPs by paeoniflorin is mediated by the activation of HSF1.

Also, thermotolerance was induced by treatment with paeoniflorin but not glycyrrhizin. Paeoniflorin had no toxic effect at concentrations as high as 80 microg/ mL. To our knowledge, this is the first report on the induction of HSPs by herbal medicines.

 

 

 

Competitive advantages

1) As a leading manufacture, Our products have been exported to Norway, Poland, Finland, Spain, UK, France, Germany, Russia, USA, Brazil, Mexico, Australia, Japan, Korea, Thailand, Indonesia, Uruguay and many other countries.
2) We offer high quality products at competitive price in quick delivery with 100% custom pass guaranteed. Never stop striving to offer our best after-sale service is our philosophy.
3) We have Flexible and Untraceable payment terms.

 


Delivery and Packing

100% Custom Pass Guarantee
Professional and Well trained Packing Team
Prompt delivery, In 24 hours delivery after payment

Packing pictures and tacking code provided in 2 days after Delivery.
24/7 after sale service.

 

 

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CONTACT US

Contact person:helena liu

coco@yuanchengtech.com

whatsapp:+86 18872220806

 

 

 

 

 

 

 

 

 

 

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