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Solvent Extraction Raw Powder Ethyl Ferulate For Preventing Ultraviolet Light Damage 4046-02-0

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Solvent Extraction Raw Powder Ethyl Ferulate For Preventing Ultraviolet Light Damage 4046-02-0

China Solvent Extraction Raw Powder Ethyl Ferulate For Preventing Ultraviolet Light Damage 4046-02-0 supplier
Solvent Extraction Raw Powder Ethyl Ferulate For Preventing Ultraviolet Light Damage 4046-02-0 supplier Solvent Extraction Raw Powder Ethyl Ferulate For Preventing Ultraviolet Light Damage 4046-02-0 supplier Solvent Extraction Raw Powder Ethyl Ferulate For Preventing Ultraviolet Light Damage 4046-02-0 supplier Solvent Extraction Raw Powder Ethyl Ferulate For Preventing Ultraviolet Light Damage 4046-02-0 supplier Solvent Extraction Raw Powder Ethyl Ferulate For Preventing Ultraviolet Light Damage 4046-02-0 supplier

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Product Details:

Place of Origin: China
Brand Name: LSW
Certification: ISO9001, SGS, USP, BP
Model Number: 4046-02-0

Payment & Shipping Terms:

Minimum Order Quantity: 10g
Price: Negotiated (Best offer will be provided based on your quantity)
Packaging Details: Professional discreet package, Foil bag or as your demand.
Delivery Time: Within 24 hours after payment
Payment Terms: Western Union, MoneyGram, Bank transfer, Bitcoin
Supply Ability: Plenty In Stock (New Batch)
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Detailed Product Description
Chemical Name: 4-Hydroxy-3-methoxycinnamic Acid Ethyl Ester M F: C12H14O4
M W: 222.24 Storage: Store In An Airtight Container, Protected From Light.
Executive Standard: Enterprise Standard Packing Specification: 25kg/drum
Email: Coco@yuanchengtech.com Whatsapp: +86 18872220806

 

Solvent Extraction Raw Powder Ethyl Ferulate For Preventing Ultraviolet Light Damage 4046-02-0

 

 

Wuhan Lianshangwang Technology Co.,LTD

Contact person:helena liu

coco@yuanchengtech.com

whatsapp:+86 18872220806

 

 

Ethyl Ferulate Details:

 

CAS 4046-02-0
Chemical name 4-Hydroxy-3-methoxycinnamic acid ethyl ester
M F C12H14O4
M W 222.24
Storage Store in an airtight container, protected from light.
Executive standard Enterprise Standard
Main index Appearance: white crystalline powder
Melting point: 63-65 °C
Loss on drying:≤ 0.10%
Assay(HPLC): ≥98.0%
Packing specification 25kg/drum

 

 

Ethyl Ferulate Description:

 

Ethyl Ferulate (4-hydroxy-3-methoxycinnamic acid, FA) is a naturally occurring plant product that has long been studied due to its potential beneficial health properties, including anti-oxidative. anti-inflammatory , neuroprotective and antiproliferative activities. The efficiency of FA as an antioxidant compound has been linked to the stability of its phenoxyl radical due to charge delocalization between the aromatic ring and the double bond in the side chain.

 

In the same direction, the alkyl ester derivative of ferulic acid, ethyl ferulate (ethyl 4-hydroxy-3-methoxycinnamate, FAEE) has also been widely studied and some recent findings include its anticholinesterase activity; inhibition of nuclear factor-kappa B (NF-κB) activity in LPS-stimulated RAW 264.7 macrophages; inhibition of inducible nitric oxide synthase (iNOS) induction in UV-induced oxidative stress in melanocytes; induction of heme oxygenase (HO-1) activity in rat astrocytes and neurons, which is a putative pathway against oxidative stress that underline neurodegenerative diseases; and cytoprotective effect against reactive oxygen species (ROS)-induced damage through the stimulation of dermal fibroblasts stress response. These potential pharmacological properties of FAEE have been related to its increased lipophilicity compared to its acid precursor, a property that could enhance the accessibility to the intracellular medium by diffusion by the cell membrane.

 

The enhanced pharmacological properties of FAEE compared to FA is not an isolated phenomenon. Indeed, the esterification of phenolic acids has widely been used as an efficient approach to improve its efficacy in several experimental models. A significant example is gallic acid, since the antimutagenicity activity against activated 2-aminoanthracene (2AA)-induced SOS responses in Salmonella typhimurium is dependent on alkyl chain length of the gallic acid alkyl esters. The antioxidant capacity, evaluated as inhibitors of AAPH-induced lyses of erythrocytes was eight-fold higher when propyl gallate was compared to gallic acid. Gallates are also more effective than their acid precursors as inhibitors of TNF-α-induced NFκB activation in human embryonic kidney cells. A similar tendency was observed to protocatechuic and caffeic acids. In this concern, findings in our laboratory have demonstrated that the heptyl ester of protocatechuic acid was ten-fold more efficient that the acid precursor as inhibitor of the production of superoxide in activated neutrophils; and the butyl and heptyl esters of caffeic acid were four-fold more effective as bactericidal agent against Helicobacter pylori.

 

 

Ethyl Ferulate Specification:

 

Item Specification
Assay 99.0% min
Specific rotation +39.5 to +41.5°
State of solution(transmittance) Clear 98.0% min.
Chloride[cl] 0.020% max.
Ammonium [NH4] 0.02% max.
Sulfate[SO4] 0.020% max
Iron[Fe] 10ppm max.
Heavy metals [Pb] 10ppm max
Arsenic[As2O3] 1ppm max
Other amino acids Chromatographically not detectable
Loss on drying 0.20% max.
Residue on ignition[sulfated] 0.10% max.

 

Solvent Extraction Raw Powder Ethyl Ferulate For Preventing Ultraviolet Light Damage 4046-02-0

 

 

Ethyl Ferulate Test Report:

 

Item Specification Results
Assay(Ferulic acid by HPLC) NLT 99.0 % 99.4%
Loss on Drying NMT 5.0% 0.42%
Sieve 100% pass 100 mesh Complies
Melting point 173-176ºC Conforms
Sulphated Ash NMT 0.1% 0.04%
Heavy Metals NMT 10ppm Conforms
Arsenic NMT 1ppm Conforms
Related Substances NMT 0.5% 0.23%
Residual Solvent Eur.Pharm Conforms
Total plate count <1000/ g 120/g
Yeast & mold <100/ g 30/g
E.coil Negative Negative
Salmonelia Negative Negative

 

 

Competitive advantages

1) As a leading manufacture, Our products have been exported to Norway, Poland, Finland, Spain, UK, France, Germany, Russia, USA, Brazil, Mexico, Australia, Japan, Korea, Thailand, Indonesia, Uruguay and many other countries.
2) We offer high quality products at competitive price in quick delivery with 100% custom pass guaranteed. Never stop striving to offer our best after-sale service is our philosophy.
3) We have Flexible and Untraceable payment terms.

 


Delivery and Packing

100% Custom Pass Guarantee
Professional and Well trained Packing Team
Prompt delivery, In 24 hours delivery after payment

Packing pictures and tacking code provided in 2 days after Delivery.
24/7 after sale service.

 

Solvent Extraction Raw Powder Ethyl Ferulate For Preventing Ultraviolet Light Damage 4046-02-0

 

 

 

 

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