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Natural Pharmaceutical Raw Materials / Formestane For Anti- Estrogen , MF C19H26O3

China Natural Pharmaceutical Raw Materials / Formestane For Anti- Estrogen , MF C19H26O3 supplier
Natural Pharmaceutical Raw Materials / Formestane For Anti- Estrogen , MF C19H26O3 supplier Natural Pharmaceutical Raw Materials / Formestane For Anti- Estrogen , MF C19H26O3 supplier Natural Pharmaceutical Raw Materials / Formestane For Anti- Estrogen , MF C19H26O3 supplier Natural Pharmaceutical Raw Materials / Formestane For Anti- Estrogen , MF C19H26O3 supplier

Large Image :  Natural Pharmaceutical Raw Materials / Formestane For Anti- Estrogen , MF C19H26O3

Product Details:

Place of Origin: China
Brand Name: LSW
Certification: ISO9001, SGS, USP, BP
Model Number: 566-48-3

Payment & Shipping Terms:

Minimum Order Quantity: 10g
Price: Negotiated (Best offer will be provided based on your quantity)
Packaging Details: Professional discreet package, Foil bag or as your demand.
Delivery Time: Within 24 hours after payment
Payment Terms: Western Union, MoneyGram, Bank transfer, Bitcoin
Supply Ability: Plenty In Stock (New Batch)
Contact Now
Detailed Product Description
Alias: Lentaron, 4-hydroxyandrost-4-ene-3,17-dione Appearance: Off-white Crystalline Powder
MF: C19H26O3 MW: 302.41
Usage: An Antitumor Drug. An Aromatase Inhibitor Dosage: 250mg, 1 Time Every Two Weeks, As The Arm Deep Intramuscular Injection.
Email: Coco@yuanchengtech.com Whatsapp: +86 18872220806

 

Selective Aromatase Inhibitor Steroid Lentaron / Formestane For Anti- estrogen

 

 

Wuhan Lianshangwang Technology Co.,LTD

Contact person:helena liu

coco@yuanchengtech.com

whatsapp:+86 18872220806

 

 

Formestane Description:

 

Formestane, also known as Lentaron, 4-hydroxyandrost-4-ene-3,17-dione, is a type I, steroidal, selective aromatase inhibitor. It is used in the treatment of estrogen receptor-positive breast cancer in postmenopausal women. The drug is not active orally, and is instead available only as an intramuscular depot injection. Because of this, it is no longer popular as many orally active aromatase inhibitors have been identified and introduced. Formestane is an analogue of androstenedione.

 

Formestane is often used to suppress the production of estrogens from anabolic steroids or prohormones. It also acts as a prohormone to 4-hydroxytestosterone, an active steroid which displays weak androgenic activity in addition to acting as a weak aromatase inhibitor.

 

Natural Pharmaceutical Raw Materials / Formestane For Anti- Estrogen , MF C19H26O3

 

Formestane Details:

 

Alias Lentaron, 4-hydroxyandrost-4-ene-3,17-dione
CAS 566-48-3
Appearance off-white crystalline powder
MF C19H26O3
MW 302.41
Usage An antitumor drug. An aromatase inhibitor
Dosage 250mg, 1 time every two weeks, as the arm deep intramuscular injection.
Density 1.19 g/cm3
Melting Point 199-202 °C
Boiling Point 475.4 °C at 760 mmHg
Flash Point 255.4 °C
Packing Foil bag or as requirments
Grade Pharmaceutical Grade

 

 

Formestane Application

 

Formestane is an aromatase inhibitor which significantly reduces plasma levels of estrogen and has shown antitumour activity in postmenopausal women with breast cancer. Objective response rates in heavily pretreated patients with advanced breast cancer generally range between 20 and 30% during treatment with intramuscular formestone 250 or 500mg once every 2 weeks, and a further 20 to 30% of patients experience disease stabilisation. The median duration of response is between 8 and 14 months. Highest response rates are observed in soft tissue metastases, in patients with estrogen-responsive tumours and in those showing a response to previous endocrine therapy. Furthermore, there is some evidence to suggest that higher response rates are achieved with formestane 500 versus 250mg once every 2 weeks. In comparative studies, the clinical efficacy of intramuscular formestane 250mg did not differ significantly from that of oral megestrol when administered as second-line endocrine therapy to patients with advanced disease in whom previous tamoxifen therapy had failed. In addition, formestane produced a response rate, duration of response and overall survival rate that was not significantly different from that of oral tamoxifen when administered as first-line endocrine therapy to patients with advanced disease, but tamoxifen was superior in some measures. Further investigation of these 2 agents, including the higher dosage of formestane 500mg, is necessary to confirm their relative efficacies.

 

 

 

Formestane Test Report:

 

Test Specification Results
Appearance White or Almost White Crystalline Powder Conforms
Melting Point 199-203ºC 201.5ºC
Loss On Drying ≤0.50% 0.32%
Specific Rotation +172~+182° +174.5~+181°
Assay ≥97 99.8%
Conclusion The specification conform with Enterprise standard
QA manager Dexin Yang Analyst Jiaojiao Chen

 


Formestane Dosages

 

Formestane was dosed at 100-200mgs per application. Users would apply it onto clean, dry skin and rub in thoroughly; usually on the thighs or upper arms. It took 1 to 5 minutes to dry.

 

 

Formestane Benefits

 

1) Formestane was originally used as an injectable for breast cancer patients, but due to its possible androgenic effects it has largely been replaced by non-steroidial AIs in the medical community. Most of its use is now is limited to the bodybuilding community since it is available as a legal dietary supplement for reducing estrogen and increasing testosterone production.


2) Although formestane can effectively reduce estrogen through oral consumption, its low oral bioavailability has lead to the development of several transdermal based products (which appear to offer higher efficacy at a lower dose).


3) Relative to 6-oxo and ATD, Formestane is a more potent aromatase inhibitor, which appears to effectively reduce natural estrogen levels by as much as 50% within several days (while higher doses may further suppress estrogen). Because of formestanes potent ability at reducing estrogen it will tend to reduce HDL levels, while increasing LDL levels, thus harming the cholesterol profile. For this reason, it is recommended to limit cycles of formestane to 8 weeks max.


4) Because formestane also has a strong affinity for the 5a-reductase enzyme it will reduce DHT levels in the body by effectively competing with testosterone for the 5a-reductase.
Formestane converts to the active androgen 4-hydroxytestosterone which has about half the anabolic potency, and about 25% of the androgenic potency as testosterone. This would suggest that fairly high doses of formestane (800-1000mg/day) could lead to some level of anabolic enhancement (although the amount required for this would surely lead to undesirably low estrogen levels).


 

Anti- estrogen Steroids for reference:

 

Tamoxifen Acetate

Clomifene Citrate

Exemestane Aromasin

Pregabalin/lyrica

Toremifene citrate

Formestan Lentaron

Letrozole Femara

Tamoxifen Citrate (Nolvadex)

Anastrozole Acetate

 

 

 

Parcel Safety Shipping and Package

 

We according to different countries, choose the safest way to ensure products to be delivered in 3 to 7 working days, and packaging based on latest customs clearance, constantly updated to ensure products clearance rate.

Our goods packing will not contain any hormone information and can be sent out from different areas of china. At present,the goods customs clearance rate we send to United states and Europe is 99%, As for Canada, Brazil of quite high buckle close rate area, we also have a new way to get through the customs. We also have completely re-send policy to some areas

At present,the goods customs clearance rate we send to United states and Europe is 99%, As for Canada, Brazil of quite high buckle close rate area, we also have a new way to get through the customs. We also have completely re-send policy to some areas.

 

If Seized by custom, we reship for free. Pls donot worry.

 

 

SBJ Powder for reference:

 

Testosterone Acetate Trenbolone Acetate
Testosterone Cypionate Trenbolone Enanthate
Testosterone Decanoate Boldenone Acetate
Testosterone Enanthate Boldenone undecylenate
Testosterone Isocaproate Boldenone Cypionate
Testosterone Phenylpropionate Boldenone Propionate
Testosterone Propionate Nandrolone Decanoate
Testosterone Undecanoate Nandrolone phenylpropionate
Mesterone Nandrolone undecylate
Testosterone Sustanon 250 Nandrolone cypionate
Clostebol Acetate Nandrolone propionate
Methylandrostanolone Methyltrienolone
Methenolone Enanthate Drostanolone Propionate
Methenolone Acetate Drostanolone Enanthate
Anadrol Stanolone
Anavar Tadalafil
Clomifene citrate Dianabol
Toremifene citrate Tamoxifen Citrate
Finasteride hydrochloride
Selank 5mg/vial DSIP 2mg/vial
MGF 2mg/vial PEG MGF 2mg/vial
CJC-1295 with DAC 2mg/vial CJC-1295 without DAC 2mg/vial
PT-141 10mg/vial MT-1 10mg/vial
MT-2 10mg/vial GHRP-2 5mg/vial
GHRP-6 5mg/vial GHRP-6 10mg/vial
Ipamorelin 2mg/vial Hexarelin 2mg/vial
Sermorelin 2mg/vial Oxytocin 2mg/vial
TB500 2mg/vial Pentadecapeptide BPC 157 2mg/vial
Triptorelin 2mg/vial Tesamorelin 2mg/vial
Gonadorelin 2mg/vial Gonadorelin 10mg/vial

 

 

 

 

For more details, freely contact me

 

Contact person:helena liu

coco@yuanchengtech.com

whatsapp:+86 18872220806

 

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