Professional Supply 99% Raw Steroid Anabolic Hormone Powders Semi-finished injection oils ,Oral oils,SARMS and Peptides.

Home
Products
About Us
Factory Tour
Quality Control
Contact Us
Request A Quote
Home ProductsPharmaceutical Raw Materials

Wuhan Lianshangwang Technology Co.,LTD

Certifications
Good quality Testosterone Steroids for sales
Good quality Testosterone Steroids for sales
Customer Reviews
I am happy so far with the raw powders. The test propionate is crystalline like its supposed to be and the test enanthate is as it should appear.

—— Alex

The product awesome , you awesome ! I am very happy for working with you.

—— Sandoval

He care the order payment more than I do , but I have to say he care my parcels much more than I do when tracking the orders !

—— Edoardo

I'm Online Chat Now

Pramipexole / Pramipexole Dihydrochloride Pharmaceutical Raw Materials for Parkinson Syndrome

China Pramipexole / Pramipexole Dihydrochloride Pharmaceutical Raw Materials for Parkinson Syndrome supplier
Pramipexole / Pramipexole Dihydrochloride Pharmaceutical Raw Materials for Parkinson Syndrome supplier Pramipexole / Pramipexole Dihydrochloride Pharmaceutical Raw Materials for Parkinson Syndrome supplier Pramipexole / Pramipexole Dihydrochloride Pharmaceutical Raw Materials for Parkinson Syndrome supplier Pramipexole / Pramipexole Dihydrochloride Pharmaceutical Raw Materials for Parkinson Syndrome supplier Pramipexole / Pramipexole Dihydrochloride Pharmaceutical Raw Materials for Parkinson Syndrome supplier Pramipexole / Pramipexole Dihydrochloride Pharmaceutical Raw Materials for Parkinson Syndrome supplier

Large Image :  Pramipexole / Pramipexole Dihydrochloride Pharmaceutical Raw Materials for Parkinson Syndrome

Product Details:

Place of Origin: China
Brand Name: coco@yuanchengtech.com
Certification: ISO,SGS
Model Number: 104632-26-0

Payment & Shipping Terms:

Minimum Order Quantity: 10g
Price: Negotiable
Packaging Details: As required
Delivery Time: 1-3 work days
Payment Terms: T/T, Western Union, MoneyGram, Bitcoin
Supply Ability: Mass Stock
Contact Now
Detailed Product Description
MF: C10H17N3S MW: 211.33
Appearance: White To Off-white Or Light Yellow Powder Assay: 99.0%~101.0%
PH: 2.8-3.4 MP: 288-290°C
Email: Coco@yuanchengtech.com Whatsapp: +86 18872220806

Pharmaceutical Grade Pramipexole / Pramipexole Dihydrochloride for Parkinson Syndrome
 

 

Wuhan Lianshangwang Technology Co.,LTD

Contact person:helena liu

coco@yuanchengtech.com

whatsapp:+86 18872220806

 

 

1) Pramipexole Details
 

Product Name

Pramipexole

Synonyms

(S)-4,5,6,7-Tetrahydro-n6-Propyl-2,6-Benzothiazolediamine;(S)-2-amino-6-propylamino-4,5,6,7-tetrahydrobenzthiazole;n'-propyl-4,5,6,7-tetrahydrobenzothiazole-2,6-diamine;pramipexol;(S)-2-Amino-6-(propylamino)-4,5,6,7-tetrahydrobenzothiazoltetrahydrobenzothiazol:

Pramipexole Dihydrochloride;Pramipexol Diclorohidrato Monohidrato

CAS

104632-26-0

EINECS

N/A

MF

C10H17N3S

MW

211.33

Molecular Structure Pramipexole / Pramipexole Dihydrochloride Pharmaceutical Raw Materials for Parkinson Syndrome

Chemical Properties

White to almost white crystalline powder

Assay 99%
Melting Point

288-290°C

Standard Enterprise standard
Usage

(S)-Pramipexole enantiomer. s disease (PD) and restless legs syndrome (RLS).[1] It is also sometimes used off-label as a treatment for cluster headache and to counteract the problems with sexual dysfunction experienced by some u sers of the selective serotonin reuptake inhibitor (SSRI) antidepressants.

Definition

ChEBI: A member of the class of benzothiazoles that is 4,5,6,7-tetrahydro-1,3-benzothiazole in which the hydrogens at the 2 and 6-pro-S-positions are substituted by amino and propylamino groups, respectively.

Packing 1KG/foil bag

 

 

 

2) Pramipexole COA:

 

 

Items Specification Results

Character

Off-white to white crystalline powder

Off-white crystalline powder

Solubility

 

Soluble in Water and Methanol, slightly soluble in Ethanol (96%), Almost insoluble in Dichloromethane

Complies

Identification

Specific Rotation -67—69.5° (on anhydrate basis)

-67.4

(2) IR:Meets the requirement.

Complies

(3) Optical purity Test

(4) Chloride Reaction

Clarity

Clear,not deeper than Y6.

PH

2.8-3.4

2.9

Related Substances

Impurity A≤0.15%

0.03%

Impurity B≤0.15%

Not detected

Impurity C ≤0.15%

0.04%

Unknown single impurity ≤0.15%

0.07%

0.1% Total Impurity≤0.5%

0.18%

Impurity D

Impurity D≤0. 5%

0.05%

Water

4.5%-6.5%

5.7%

Heavy metals

≤10ppm

complies

Sulfate Ash

≤0.1%

0.04%

Assay

99.0%~101.0%

99.4%

 


 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Pramipexole / Pramipexole Dihydrochloride Pharmaceutical Raw Materials for Parkinson Syndrome

 

3) Drug for Treatment of Parkinson Syndrome

 

Pramipexole hydrochloride is a kind of drugs for treatment of Parkinson syndrome. It belongs to selective non-ergot dopamine receptor agonist. It was first successfully developed by Boehringer Ingelheim Company (Germany). It is a prescription drugs of dopamine receptor agonist applied in the largest amount of the world. In May, 1997, it had been approved for the first time by FDA for the treatment of idiopathic Parkinson's disease. It can reduce the symptoms and sign, and can either be used alone or in combination with levodopa. The trade name of the good marketed in the United States is Mirapex, which is the first drugs approved the FDA during the past six years for treatment of Parkinson syndrome. In 2007, it has entered into market in China with the commodity name being sifrol for the treatment of the signs and symptoms of idiopathic Parkinson's disease, being used either alone (without levodopa) or in combination with levodopa.
The two major efficacy characteristics of pramipexole hydrochloride in treatment of Parkinson's disease:
A. It can relieve the motor symptoms of Parkinson's disease: Parkinson's disease is cause due to the dopamine deficiency resulting from the loss of dopaminergic neuron, leading to patients get a series of symptoms such as tremors, muscle rigidity, slow movement and so on. Pramipexole hydrochloride can highly selective act on dopaminergic D2 and D3 receptors, thereby, stimulating the release of dopamine in the brain and alleviating the motor symptoms. Shannon et al have shown that early Parkinson's disease patients who has received pramipexole monotherapy can effectively have their motor symptoms be within control and can maintain daily living. When being used in combination with levodopa, pramipexole can effectively improve both the ADL score and the motor symptoms score of patients with advanced Parkinson's disease, and thus making the life of the patients with advanced Parkinson's disease more active.
B. it can significantly alleviate the depressive symptoms associated with Parkinson's disease: the pramipexole hydrochloride is a kind of agonists of dopamine D2, D3 receptor. The dopamine D3 receptor system may be associated with the patient's mood and behavior. Since pramipexole can selectively stimulate the D3 receptor with a higher agonist efficacy than D2 receptors, it can significantly relieve symptoms of depression. In study of Barone (Italy) et al, when patients with Parkinson’s disease had been treated with pramipexole or sertraline, the proportion of patients with alleviated depression symptoms in pramipexole group was significantly higher than that of the sertraline group. Researchers believe that dopamine agonists (pramipexole) can substitute antidepressants to treat the depression of patients with Parkinson disease.
Pramipexole has protective effect on damaged neurons as well as excellent control of the jitter symptom. It has the least side effects in the field of Parkinson syndrome. Moreover, it has a large scope for adjusting drug in later phase, which is good for the following treatment. It can prevent the nerve damage caused by long-term use of levodopa, delaying the time needed for levodopa treatment as well as reducing the dose of levodopa.

 

 

4) Recommend Products:

 

Pain Killer Benzocaine / Benzocaine HCL
Procaine / Procaine HCL
Lidocaine Base/ Lidocaine HCL

Tetracaine / Tetracaine HCL

Prilocaine
Articaine HCL

Pharmaceuticals Phenacetin
Dexamethasone Sodium Phosphate
Isotretinoin
Pregabalin
GBL
Furazabol THP
Lorcaserin
Carbergoline
Safe Organic Solvents 1,4-Butanediol(BDO)
Ethyl Oleate(EO)
Grape Seed Oil(GSO)
Benzyl Alcohol(BA)
Benzyl benzoate(BB)
Guaiacol
SARMs Aicar
Andarine / S4
Andarine / GTX-007
GW-501516(cardarine)
LGD-4033
MK-677/Ibutamoren/Nutrobal
MK-2866/Ostarine
RAD-140
SR9011
SR9009
Sunifiram
YK11


 

5) Pramipexole Functions and Traits

Pramipexole is a dopamine agonist that directly correlates with the prolactin hormone. As dopamine levels in the body go up, prolactin levels go down. It does this by having a direct effect on the dopamine D3 receptor. Although it also acts on the D2 receptor its affinity for the D3 receptor is seven times greater than any existing dopamine agonist.

The effect of Pramipexole on the D3 receptor has a strong impact on the neurological system, which is why it's used to treat Parkinson's disease and in some cases Alzheimer's disease. Through acting on the D3 receptor, Pramipexole also affects a man's sexual interest and activity. Prolactin is in part directly responsible for a man's refractory period, which refers to the time it takes to recover from sexual activity so that performance can occur again. By lowering prolactin through an increase in dopamine, Pramipexole can directly reduce the refractory period resulting in the ability to perform sexually more frequently.

 

 

 

Thank you for interested in our product.

We are the professional manufacturer over 15 years, good reputation in the globe trade.

Most of our product are USP standard, and available anytime; good quality and high purity you should enjoy.

It's important for you to choose a business partner who can offer a competitive price

 

CONTACT US

coco@yuanchengtech.com

whatsapp:+86 18872220806

Contact Details
Wuhan Lianshangwang Technology Co.,LTD

Contact Person: Cindy Steroids

Send your inquiry directly to us (0 / 3000)