GHRP-2 release peptide-2 GHRP-2
GHRP-2 and Ipamorelin are all very similar in their modes of action, they work to increase GHRP-2 (GH) levels in the human body by increasing secretion of the hormone Ghrelin. On a milligram for milligram basis they are all fairly equal in their ability to increase GH levels in the human body, with GHRP-2 being slightly more efficient.
The major differences between the 3 GHRP peptides lays in their side effects. GHRP-6 causes a significant increase in hunger for many, therefore making it good for people looking to "bulk" but no so good for those trying to lose fat. GHRP-2 is often preferred for people dieting as it does not stimulate hunger, however it does raise cortisol (a stress hormone), prolactin (a hormone which can diminish sex drive) and aldosterone (a hormone which promotes water retention) more than GHRP-6 and Ipamorelin. Ipamorelin is similar to GHRP-6 in that it causes an increase in hunger (but it's not as dramatic as GHRP-6). However, since it does not raise cortisol, prolactin or aldosterone at recommended dosages it is a preferred choice for those who are sensitive to these hormones.
Frequently asked Questions
Q: Why use GHRP2 instead of GHRP-2?
A: This can be used alone or as an adjunct to HGH therapy. Both methods will yield robust results. The synergy of using GHRP2 with injectable GHRP-2 is that it allows your own natural production to remain and rebuild along with the use of injectable GHRP-2. GHRP2 works greatly on it's own as well.
Q: I have heard of using GHRP-2 orally and don't have much faith in this manner of its application. Can you explain about this?
A: GHRP-2 has a brief half life and is rendered ineffective when orally applied, swallowed and passed into the gastric tract. Then it must pass through the liver when applied orally. This is why HGH is effectively administered through subcutaneous injections. Conversely, GHRP2 oral mucosal medicine delivery i.e.: sublingual/ intranasal as demonstrated in clinical studies, is an effective alternative method of systemic medicine /supplement delivery that offers not only impressive results - but several advantages over both injectable and enteral methods.
Because the oral mucosa is highly vascularised, medi-suppliments that are absorbed through the oral mucosa directly enter the systemic circulation, bypassing the gastrointestinal tract and first pass metabolism in the liver. For some supplements and drugs, this results in rapid onset of action via a more comfortable and convenient delivery route than the intravenous route. Not all medications, however, can be administered through the oral mucosa because of the characteristics of the oral mucosa and the physicochemical properties of the supplement.
GHRP2 can be delivered sublingual and is the preferred method of application - and in a peer reviewed clinical study from the Department of Pediatrics at the University of Arkansas for Medical Sciences, published in the Journal of Endocrinology and Metabolism in 1995, "All 15 children had a significant GH response to 15 pg/kg dose. The intranasal /mucosa delivery was well tolerated."
GHRP2 adult therapy benefits
Improve sex drive and desire by stimulation of hypothalamus
Reduces belly fat through lipolysis
Increases energy and vitality
Improves skin elasticity, ridding wrinkles
Accelerates healing from wounds or surgery
Strengthens the heart
Enhances the immune system
Increases IGF-1 production, by as much as
50% in first week
Improves sleep quality
Increases calcium retention, strengthens and increases the mineralization of bone, bone density
Increases protein synthesis,
Improves eyesight and vision
Reduces liver uptake of glucose, an effect that opposes that of insulin
Promotes liver glucogenesis
Contributes to maintenance and function of pancreatic islets
GHRPs are a small family of peptides acting at the pituitary and the hypothalamus to release GHRP-2 (GH) through the activation of a specific, G protein-coupled receptor.
They were discovered 20 years ago as synthetic metenkephalin- derived oligopeptides (Synthetic tissue derived amino acids). Although it has no structural homology with GHRP-2 Releasing Hormone (GHRH), in clinical studies GHRP-2 demonstrated action on the pituitary to release Human GHRP-2 (HGH). Similar results were effective when GHRP-2 was administered sublingual. Clinical studies showed the most potent GHRP being the hexapeptide GHRP-2.
GHRP-2 Releasing Peptide 2(GHRP2) substantially stimulates the pituitary gland's increased natural production of the body's own endogenous human GHRP-2 (HGH). This therapy consists of daily periodic sub-lingual dosing. GHRP-2 releasing peptide 2, GHRP2 has shown on it's own to robustly increase IGF-1 levels, and even greater results occurred when used with GHRP-2 Releasing Hormone (GHRH) to which also stimulates the pituitary gland to produce increased natural secretion of human GHRP-2. This also boosts the hypothalamus function as well.