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|Standard:||Enterprise Standard||Appearance:||Brown Yellow Powder|
Effective Body Slimming Yellow Powder DNP / Sodium 2,4-Dinitrophenolate for Gain Muscle
1) DNP Details
|Product Name||Sodium 2,4-dinitrophenate|
Sodium 2,4-dinitrophenate;Sodium-2,4-dinitrophenol;Sodium 2,4-dinitrophenolate;2,4-dinitrophenol sodium salt;2,4-dinitrophenol,
|Character||Brown yellow powder|
|Usage||Commercial DNP is used as an antiseptic and as a pesticide. It is a chemical intermediate in the production of sulfur dyes, wood preservatives, and some herbicides including dinoseb and dinoterb. DNP has also been used to make photographic developers and explosives.|
2) DNP Function
When exceeding label-specified maximum dosages, dextromethorphan acts as a dissociative hallucinogen. Its mechanism of action is via multiple effects, including actions as a nonselective serotonin reuptake inhibitor and a sigma-1 receptor agonist. The major metabolite of DXM, dextrorphan, also acts as an NMDA receptor antagonist. In high doses this produces effects similar to, yet distinct from, the dissociative states created by other dissociative anaesthetic. As well, the metabolite 3-methoxymorphinan of dextrorphan (thus a second-level metabolite of DXM) produces local anesthetic effects in rats with potency above dextrorphan, but below that of DXM.
3) DNP Application
2, 4-Dinitrophenol (2, 4-DNP, or simply DNP) is an organic compound with the formula HOC6H3(NO2)2.
It is a yellow, crystalline solid that has a sweet, musty odor. It sublimes, is volatile with steam, and is soluble in most organic solvents as well as aqueous alkaline solutions. It is a precursor to other chemicals and is biochemically active, inhibiting energy (ATP) production in cells with mitochondria and was once used as a diet aid. It is produced by hydrolysis of 2, 4-dinitrochlorobenzene.
DNP was used extensively in diet pills from 1933 to 1938 after Cutting and Tainter at Stanford University made their first report on the drug's ability to greatly increase metabolic rate. After only its first year on
the market Tainter estimated that probably at least 100, 000 persons had been treated with DNP in the United States, in addition to many others abroad. DNP acts as a protonophore, allowing protons to leak across the inner mitochondrial membrane and thus bypass ATP synthase. This makes ATP energy production less efficient. In effect, part of the energy that is normally produced from cellular respiration is wasted as heat. The inefficiency is proportional to the dose of DNP that is taken. As the dose increases and energy production is made more inefficient, metabolic rate increases (and more fat is burned) in order to compensate for the inefficiency and meet energy demands. DNP is probably the best known agent for uncoupling oxidative phosphorylation. The production or "phosphorylation" of ATP by ATP synthase gets disconnected or "uncoupled" from oxidation.
4) Biochemical Aspects
In living cells, DNP acts as a proton ionophore, an agent that can shuttle protons (hydrogen cations) across biological membranes. It dissipates the proton gradient across mitochondria and chloroplast membranes, collapsing the proton motive force that the cell uses to produce most of its ATP chemical energy. Instead of producing ATP, the energy of the proton gradient is lost as heat.
DNP is often used in biochemistry research to help explore the bioenergetics of chemiosmotic and other membrane transport processes.
5) Health Effects
DNP is considered to have high acute toxicity. Acute oral exposure to DNP has resulted in increased basal metabolic rate, nausea, vomiting, sweating, dizziness, headache, and loss of weight. Chronic oral exposure to DNP can lead to the formation of cataracts and skin lesions and has caused effects on the bone marrow, central nervous system, and cardiovascular system.
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1, 3-Dimethylbutylamine Hydrochloride
6) More About Us
A) Do you charge for the samples?
S: According to our company policy, we just charge the samples based on EXW price. And we will return the samples fee during the next order.
B) How can I be sure the powder contains right substances?
S: We can offer you the cretificate of analysis of products and HPLC, Besides, After Receiving the goods, you can send it to detect, or buy a test kit steroid, detect it by yourself.
C) Can you tell me more details about the packing?
S: Sure,we will adopt safe and discreet package. And we can give you the pictures of the packing for your reference. Of course, If you have a request for packing, please tell us, Any good ideas are welcomed.
D) What's the guarantees that you will send items after payment?
S: We have been in business for many years. You can check our paid website. We spend many money to make our business, not only for the little benefits. Moreover, the tracking numbers and packing details will be informed to you asap, you can keep track of it.so,don't hesitate to let me serve you.