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ACVR2B ACE-031 Human Growth Hormone Peptides Polypeptide Lyophilized Powder
|Physical State||White Powder|
|Usage||Bodybuilding ;Myostatin Blockers|
ACVR2B (ACE-031) body-building Purity:98% Activin Receptor Type IIB
ACE-031 is intended for research purpose only. ACE-031 should not be used for human
consumption, diagnostic, therapeutic procedures, agricultural and veterinary purposes.
ACE-031 is a soluble fusion protein that has been shown to increase muscle mass and
strength in research studies. ACE-031 is being studied as a treatment for metabolic diseases,
renal neoplasms of childhood, cardiovascular anomalies, age-related muscle loss, and cancer
treatment related muscle loss and neuromuscular diseases. ACE-031 is a biologic therapeutic,
based on activin receptor type IIB (ActRIIB). The molecule inhibits signaling via the ActRIIB
receptor binding and increase muscle mass and strength. ACE-031 is a recombinant fusion
protein that is artificially synthesized by fusion of standard antibody and a portion of ActRIIB
receptor. The recombinant fusion protein eliminates myostatin and other biomolecules that limit
muscle strength or growth.
ACE-031 belongs to class of proteins of TGF-beta super family that regulate muscle growth.
ACE-031 acts on the molecular switches of these molecules and promote muscle growth.
In experimental studies, ACE-031 promotes muscle growth and inhibits ActRIIB receptor
signaling. In pre-clinical studies, administration of ACE-031 for two weeks increased skeletal
muscle density, decreased leptin levels, and increased adiponectin.
Some bodybuilders use ACE-031 to promote muscle growth and to improve lean muscle.
No serious adverse events were reported after ACE-031. Most of the common adverse events
are mild and tolerable. The polypeptide contains 368 amino acid molecules, which forms a very
large polypeptide complex. Muscle growth is regulated by the production of amino acids , and
TGF beta protein super family is mainly the regulator as indicated earlier the on and off switch
mechanism is essential for muscle production. When ActRIIB receptors interact with the GDF-8, it
sends an on signal, which in turn promotes muscle growth.
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