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|Appearance:||White To Off-white Crystalline Solid||Email:||Coco@yuanchengtech.com|
Male Enchancement Steroids HCl 129938-20-1
Wuhan Lianshangwang Technology Co.,LTD
Contact person:helena liu
|Molecular Formula||C21H23NO HCl|
|Storage||Keep it under seal in cool and dark place|
|Appearance||This product is White to off-white crystalline solid, odorless, sweet, soluble in water, alcohol.|
|Usage||() as a new fast SSRI, a short half life, a selective 5 - HT reuptake inhibitor (SSRI), for the treatment of premature ejaculation and erectile dysfunction. is a selective 5 - HT reuptake inhibitor (SSRI), such drugs widely used to treat depression and related affective disorders|
|Package||1kg/aluminum foil bag|
|Character||White to Off-White Cyrstalline Solid, odorless, slight sweet taste, Mp 175-177°C, optical rotation +128°
|Characteristics||White or almost white crystalline powder||White crystalline powder|
|Loss on drying||≤0.5%||0.32%|
|Assay(on drled basis)||≥99.5%||99.61%|
|Conclusion||It complies to prescribed enterprise standard|
What is ?
hydrochloride, belonging to a class of drugs known as selective serotonin reuptake inhibitors or, was the first drug originally approved for the on-demand treatment of men with PE. We aimed to compare the intravaginal ejaculatory latency time (IELT), patient-reported global impression of change (PGIC), and adverse effect (AE) incidence associated with the use of (30mg and 60mg) versus placebo, and evaluate the differences in administering 60mg versus 30mg as on-demand medical oral therapy for the treatment of PE via a literature review and meta-analysis. Relevant randomized controlled trials (RCTs) were identified from PubMed, EMBASE, and Cochrane Central Register of Controlled Trials (Cochrane Library) databases. Ultimately, a total of seven RCTs with 8039 patients were included. Our meta-analysis demonstrated that (in the 30mg and 60mg subgroup) resulted in significantly higher IELT, PGIC, and AE incidence relative to the placebo, with higher proportions observed for 60mg versus 30mg of administration. The most common AEs were mild and tolerable. We conclude that (particularly the 60mg dosage) may be considered a safe and effective drug for patients with PE.
Effects for ED treatment:
Treat male premature ejaculation and erectile dysfunction.
Because lack of specific approval treatment for PE in the US and some other countries, other SSRIs such as fluoxetine, paroxetine, sertraline, fluvoxamine, and citalopram have been used as off label drugs to treat PE. Waldinger's meta analysis shows that the use of these conventional antidepressants increasing IELT from two to ninefold above base line in comparison of three to eightfold when is used. However, these SSRIs must be taken daily in order to achieve meaningful efficacy, and the long half-life increases the risk of the drug accumulation and as a consequence increased of adverse effects such as decreasing sexual libido and causing erectile dysfunction. , on the other hand, is a fast acting SSRI. It is rapidly absorbed and eliminated from the body within a few hours. This favorable pharmacokinetics minimizes the risk of the drug's accumulation in the body, and therefore reducing side effects.
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