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Lidocaine cas 137-58-6

China Lidocaine  cas  137-58-6 supplier
Lidocaine  cas  137-58-6 supplier Lidocaine  cas  137-58-6 supplier Lidocaine  cas  137-58-6 supplier Lidocaine  cas  137-58-6 supplier

Large Image :  Lidocaine cas 137-58-6

Product Details:

Place of Origin: China
Brand Name: YC
Certification: ISO9001
Model Number: 137-58-6

Payment & Shipping Terms:

Minimum Order Quantity: 10g
Price: Negotiated (Best offer will be provided based on your quantity)
Packaging Details: Professional discreet package, Foil bag or as your demand.
Delivery Time: Within 24 hours after payment
Payment Terms: Western Union, MoneyGram, T/T
Supply Ability: 3000kg/Week
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Detailed Product Description
CAS: 137-58-6 Assays: 99.5%
Packaging: 25kg/drum Molecular Formula: C14H23N2O
Molecular Weight: 235.3447 EINECS: 205-302-8
Appearance: White Crystal Email: Coco@yuanchengtech.com
Whatsapp: +86 18872220806

Lidocaine

Lidocaine CAS: 137-58-6
Lidocaine Assays: 99%
Lidocaine Packaging: 25kg/drum
Lidocaine Molecular Formula: C14H23N2O
Lidocaine Molecular Weight: 235.3447
Lidocaine EINECS: 205-302-8
Lidocaine Appearance: White crystal


Our advantages:
1. High quality products with competitive prices
2. Professional service
3. Enough stock and Fast delivery
 
Lidocaine  cas  137-58-6


Description:

Lidocaine is a common local anesthetic and class-1b antiarrhythmic drug. Lidocaine is used topically to relieve itching, burning, and pain from skin inflammations, injected as a dental anesthetic, or used as a local anesthetic for minor surgery. It replaces procaine,being widely used in plastic and cosmetic operation in local infiltration anesthesia, the sodium channel inhibition of the nerve cell membrane to block nerve excitability and conduction.
It is on the World Health Organization's List of Essential Medicines, a list of the most important medications needed in a basic healthcare system


Application:

The efficacy profile of lidocaine as a local anesthetic is characterized by a rapid onset of action and intermediate duration of efficacy. Therefore, lidocaine is suitable for infiltration, block, and surface anesthesia. Longer-acting substances such as bupivacaine are sometimes given preference for subdural and epidural anesthesias; Lidocaine, though, has the advantage of a rapid onset of action. Epinephrine vasoconstricts arteries, reducing bleeding and also delays the resorption of lidocaine, almost doubling the duration of anaesthesia. For surface anesthesia, several available formulations can be used e. G. For endoscopies, before intubations, etc. Buffering the pH of lidocaine makes local freezing less painful. Lidocaine drops can be used on the eyes for short ophthalmic procedures.

Lidocaine crosses the blood-brain and placental barriers, presumably by passive diffusion.
Lidocaine is metabolized rapidly by the liver, and metabolites and unchanged drug are excreted by the kidneys. Biotransformation includes oxidative N-dealkylation, ring hydroxylation, cleavage of the amide linkage, and conjugation. N-dealkylation, a major pathway of biotransformation, yields the metabolites monoethylglycinexylidide and glycinexylidide. The pharmacological/toxicological actions of these metabolites are similar to, but less potent than, those of Lidocaine. Approximately 90% of Lidocaine administered is excreted in the form of various metabolites, and less than 10% is excreted unchanged. The primary metabolite in urine is a conjugate of 4-hydroxy-2, 6-dimethylaniline.



Packaging & Delivery Process:

1. Delivery : Parcels would be arranged within 12 hours upon receipt your payment .
2. Packing : Steroids powders would be packed discreetly enough to cross customs
3. worldwide safely . Packing like traditional chinese food , washing and bathing items and other equipments, etc...
4. Extra service : Photos of of package would be provided for you to tell apart the steroids .
5.Tracking number would be offered once it is released .
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Certificate Of Authenticity
Product Name
Lidocaine Hydrochloride
Other Name
Lidocaine hcl
Testing Method
USP
Assay
≥99.8%
Characters
White Crystalline Powder
Cas No.
73-78-9
Molecular Formula
C 14 H 23 ClN 2 O
Molecular Weight
270.7982
Applications
1. Local anesthetic.
2. Treating Epilepsy.
3. Treating Asthma.
Packing
1kg or 5kg/bag, 25kg/drum
Shelf Life
24 months
Storage
Store in sealed containers at cool & dry place. Protect from light, moisture and pest
infestation.




Lidocaine - Clinical Pharmacology
Mechanism of action:
Lidocaine stabilizes the neuronal membrane by inhibiting the ionic fluxes required for the initiation and conduction of impulses, thereby effecting local anesthetic action.


Hemodynamics:
Excessive blood levels may cause changes in cardiac output, total peripheral resistance, and mean arterial pressure. With central neural blockade these changes may be attributable to block of autonomic fibers, a direct depressant effect of the local anesthetic agent on various components of the cardiovascular system and/or the beta-adrenergic receptor stimulating action of epinephrine when present. The net effect is normally a modest hypotension when the recommended dosages are not exceeded.


Pharmacokinetics and metabolism:
Information derived from diverse formulations, concentrations and usages reveals that Lidocaine is completely absorbed following parenteral administration, its rate of absorption depending, for example, upon various factors such as the site of administration and the presence or absence of a vasoconstrictor agent. Except for intravascular administration, the highest blood levels are obtained following intercostal nerve block and the lowest after subcutaneous administration.


Indications and Usage for Lidocaine:
Lidocaine Hydrochloride Injection, USP is indicated for production of local or regional anesthesia by infiltration techniques such as percutaneous injection and intravenous regional anesthesia by peripheral nerve block techniques such as brachial plexus and intercostal and by central neural techniques such as lumbar and caudal epidural blocks, when the accepted procedures for these techniques as described in standard textbooks are observed.


 

 

 

 

 

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coco@yuanchengtech.com

whatsapp:+86 18872220806

 

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