Professional Supply 99% Raw Steroid Anabolic Hormone Powders Semi-finished injection oils ,Oral oils,SARMS and Peptides.
Professional Supply 99% Raw Steroid Anabolic Hormone Powders Semi-finished injection oils ,Oral oils,SARMS and Peptides.
Product Details:
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| Product Name: | Aicar | Other Name: | Acadesine |
|---|---|---|---|
| CAS Number: | 2627-69-2 | M.F.: | C9h14n4o5 |
| M.W.: | 258.23 | Packaging: | Foil Bag Or Vial |
| Appearance: | White Crystalline Powder | Assays: | 99% |
| Shipping: | By Express (FedEx,UPS,DHL,EMS), By Air And By Sea | Payment: | Money Gram, T/T And Paypal |
| Email: | Cayla@ycgmp.com | WhatsApp: | +8618872220724 |
| Skype: | +8618872220724 | ||
| High Light: | sarms powder,pharmaceutical grade powder |
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Product Details
Acadesine
Alias: AICAR; AICA-RIBOSIDE; AMPK; Z-RIBOSIDE
CAS: 2627-69-2
EINECS: 220-097-5
Molecular Formula: C9H14N4O5
Molecular Weight: 258.23
Assay: 99%
Apperance: White or off-white powder.
Usage: Pharmaceutical intermediates. For the treatment of cardiovascular diseases
AICAR is a cell permeable activator of AMP-activated protein kinase (AMPK), a metabolic master regulator that is activated in times of reduced energy availability (high cellular AMP:ATP ratios) and serves to inhibit anabolic processes. In vivo, pharmacologic activation of AMPK with AICAR mimics exercise and triggers insulin-independent glucose uptake by skeletal muscle.
AMP-activated protein kinase (AMPK) functions as a metabolic sensor that regulates lipid and glucose metabolism to maintain cellular energy homeostasis and to protect against metabolic stress.AICAR is a selective activator of AMPK in both hepatocytes and adipocytes. At 0.5 mM it inhibits the synthesis of fatty acids and sterols and inactivates HMG-CoA reductase in rat hepatocytes.AICAR (0.5 mM) inhibits insulin-stimulated glucose uptake to 62% of controls and reduces GLUT4 translocation 2.5-fold in 3T3-L1 adipocytes. It also blocks the expression of pro-inflammatory cytokines (TNF-α/IL-1β and IL-6), iNOS, COX-2, and MnSOD genes in glial cells and macrophages by inhibiting NFKB and C/EBP pathways.
Cell-permeable, allosteric activator of AMP-activated protein kinase (AMPK). Augments proliferation, differentiation and mineralization of osteoblastic MC3T3-EI cells and attenuates psychosine-induced expression of proinflammatory cytokines and iNOS in astrocytes. Promotes osteogenic differentiation of hAMSCs and BM-MSCsin vitro.
Specification:
| Item | Specification | Result |
| Appearance | White powder | Complies |
| Related substance (HPLC) | Total impurity ≤0.5% Max single impurity ≤0.1% |
0.2% 0.06% |
| Odor | Characteristic | Complies |
| Assay | 99% | 99.8% |
| Sieve analysis | 100% pass 80 mesh | Complies |
| Loss on Drying Residue on Ignition |
≤1.0% ≤1.0% |
0.12% 0.09% |
| Heavy Metal | <10ppm | Complies |
| As | <0.1ppm | 0.05ppm |
| Pb | <0.1ppm | 0.05ppm |
| Cd | <0.1ppm | 0.05ppm |
| Residual Solvents | <100ppm | Complies |
| Residual Pesticide | Negative | Complies |
| Microbiology | ||
| Total Plate Count | <1000cfu/g | Complies |
| Yeast & Mold | <100cfu/g | Complies |
| E.Coli | Negative | Complies |
| Salmonella | Negative | Complies |
Contacts Infomation
Contacts: Cayla
Skype: 983165428@qq.com
E-mail: cayla@ycgmp.com
WhatsApp: +86 18219253670
