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Synthetic Anabolic Steroids Aicar Acadesine Cardiovascular Diseases Treatment

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Synthetic Anabolic Steroids Aicar Acadesine Cardiovascular Diseases Treatment

China Synthetic Anabolic Steroids Aicar Acadesine Cardiovascular Diseases Treatment supplier
Synthetic Anabolic Steroids Aicar Acadesine Cardiovascular Diseases Treatment supplier Synthetic Anabolic Steroids Aicar Acadesine Cardiovascular Diseases Treatment supplier Synthetic Anabolic Steroids Aicar Acadesine Cardiovascular Diseases Treatment supplier Synthetic Anabolic Steroids Aicar Acadesine Cardiovascular Diseases Treatment supplier Synthetic Anabolic Steroids Aicar Acadesine Cardiovascular Diseases Treatment supplier

Large Image :  Synthetic Anabolic Steroids Aicar Acadesine Cardiovascular Diseases Treatment

Product Details:

Place of Origin: China
Brand Name: cayla@ycgmp.com
Certification: GMP; ISO; SGS
Model Number: 2627-69-2

Payment & Shipping Terms:

Minimum Order Quantity: 10 G
Price: 295 USD / 10G
Packaging Details: vial and foil bag
Delivery Time: Within 24hours after received your payment
Payment Terms: T/T, Money Gram, Paypal
Supply Ability: 1000kg/mouth
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Detailed Product Description
Product Name: Aicar Other Name: Acadesine
CAS Number: 2627-69-2 M.F.: C9h14n4o5
M.W.: 258.23 Packaging: Foil Bag Or Vial
Appearance: White Crystalline Powder Assays: 99%
Shipping: By Express (FedEx,UPS,DHL,EMS), By Air And By Sea Payment: Money Gram, T/T And Paypal
Email: Cayla@ycgmp.com WhatsApp: +8618872220724
Skype: +8618872220724
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Synthetic Anabolic Steroids Aicar Acadesine Cardiovascular Diseases Treatment


Product Details

Acadesine
Alias: AICAR; AICA-RIBOSIDE; AMPK; Z-RIBOSIDE
CAS: 2627-69-2
EINECS: 220-097-5
Molecular Formula: C9H14N4O5
Molecular Weight: 258.23
Assay: 99%
Apperance: White or off-white powder.
Usage: Pharmaceutical intermediates. For the treatment of cardiovascular diseases

AICAR is a cell permeable activator of AMP-activated protein kinase (AMPK), a metabolic master regulator that is activated in times of reduced energy availability (high cellular AMP:ATP ratios) and serves to inhibit anabolic processes. In vivo, pharmacologic activation of AMPK with AICAR mimics exercise and triggers insulin-independent glucose uptake by skeletal muscle.
Synthetic Anabolic Steroids Aicar Acadesine Cardiovascular Diseases Treatment
AMP-activated protein kinase (AMPK) functions as a metabolic sensor that regulates lipid and glucose metabolism to maintain cellular energy homeostasis and to protect against metabolic stress.AICAR is a selective activator of AMPK in both hepatocytes and adipocytes. At 0.5 mM it inhibits the synthesis of fatty acids and sterols and inactivates HMG-CoA reductase in rat hepatocytes.AICAR (0.5 mM) inhibits insulin-stimulated glucose uptake to 62% of controls and reduces GLUT4 translocation 2.5-fold in 3T3-L1 adipocytes. It also blocks the expression of pro-inflammatory cytokines (TNF-α/IL-1β and IL-6), iNOS, COX-2, and MnSOD genes in glial cells and macrophages by inhibiting NFKB and C/EBP pathways.

Cell-permeable, allosteric activator of AMP-activated protein kinase (AMPK). Augments proliferation, differentiation and mineralization of osteoblastic MC3T3-EI cells and attenuates psychosine-induced expression of proinflammatory cytokines and iNOS in astrocytes. Promotes osteogenic differentiation of hAMSCs and BM-MSCsin vitro.

Synthetic Anabolic Steroids Aicar Acadesine Cardiovascular Diseases Treatment

Specification:

Item Specification Result
Appearance White powder Complies
Related substance (HPLC) Total impurity ≤0.5%
Max single impurity ≤0.1%
0.2%
0.06%
Odor Characteristic Complies
Assay 99% 99.8%
Sieve analysis 100% pass 80 mesh Complies
Loss on Drying
Residue on Ignition
≤1.0%
≤1.0%
0.12%
0.09%
Heavy Metal <10ppm Complies
As <0.1ppm 0.05ppm
Pb <0.1ppm 0.05ppm
Cd <0.1ppm 0.05ppm
Residual Solvents <100ppm Complies
Residual Pesticide Negative Complies
Microbiology    
Total Plate Count <1000cfu/g Complies
Yeast & Mold <100cfu/g Complies
E.Coli Negative Complies
Salmonella Negative Complies

 

Contacts Infomation

Contacts: Cayla

Skype: 983165428@qq.com

E-mail: cayla@ycgmp.com

WhatsApp: +86 18219253670

Contact Details
Wuhan Lianshangwang Technology Co.,LTD

Contact Person: Cindy Steroids

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