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Purity: | 99% | Appearance: | White Or Almost White Or Pale Yellow Crystalline Powder |
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Storage: | Shading, Confined Preservation | Whatsapp: | +8613026161792 |
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Mifepristone Synthetic steroids Powder RU 486 Mifeprex 84371-65-3
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Mifepristone COA
CAS No. | 84371-65-3 | Outer Packing | 1KG/drum | |
Production date | 2016.09.04 | Shelf life | 2019.09.03 | |
Standard adopted | CP 2010/Enterprise standard | |||
Items of analysis | Specification | Results | ||
Description | Light Yellowish Crystalline Powder | Light Yellowish Crystalline Powder | ||
Identification | the maximum absorption wavelength of 304nm, 260nm, and infrared absorption spectra were consistent with the control product. | Conformity | ||
Melting Point | 192ºC~196ºC 192ºC~196ºC |
192ºC~196ºC 192ºC~196ºC |
||
Specific Rotation | +124°~ +129° +124°~ +129° |
+127.3° +127.3° |
||
Single Impurity | ≤0.5% ≤0.5% |
0.45% 0.45% |
||
Total Impurity |
≤1.0% ≤1.0% |
0.60% 0.60% |
||
Loss On Drying | ≤0.5% ≤0.5% |
0.2% 0.2% |
||
Assay | ≥98.5% ≥98.5% |
99.4% 99.4% |
||
Sieve analysis | ≤30μm ≤30μm |
Conformity | ||
Conclusion | This product conforms to the CP 2010 and enterprise internal control standards |
Mifepristone Basic Info:
CAS No.: 84371-65-3
Molecular Formula: C29H35NO2
Molecular Weight: 429.65
Purity: 99%min
Appearance: White or almost white or pale yellow crystalline powder
Density: 1.18 g/cm3
Boiling Point: 628.6 ° C at 760 mmHg
Refractive Index: 1.623
Grade: Pharmaceutical Grade
Storage: Shading, confined preservation
What is Mifepristone?
Mifepristone (or RU-486) is a synthetic steroid compound with both antiprogesterone and antiglucocorticoid properties. The compound is a 19-nor steroid with substitutions at positions C11 and C17 (17 beta-hydroxy-11 beta-[4-dimethylamino phenyl] 17 alpha-[1-propynyl]estra-4, 9-dien-3-one), which antagonizes cortisol action competitively at the receptor level.
Mifepristone was the first antiprogestin to be developed and it has been evaluated extensively for its use as an abortifacient. The original target for the research group was the discovery and development of compounds with antiglucocorticoid properties. These antiglucocorticoid properties are of great interest in the treatment of severe mood disorders and psychosis, although a review of published articles was inconclusive on their efficacy, and considered the use of these drugs in mood disorders at 'proof of concept' stage. It is on the WHO Model List of Essential Medicines
Mifepristone Application:
Mifepristone (also known as RU 486) is used to cause an abortion during the early part of a pregnancy. It is used up to week 10 of pregnancy (up to 70 days after the first day of your last menstrual period). Mifepristone blocks a natural substance (progesterone) that is needed for your pregnancy to continue. It is usually used together with another medicine called misoprostol.
Precautions:
Mifepristone must not be used if you have a rare abnormal pregnancy that is outside the womb (ectopic pregnancy). It will not cause an abortion in this case. It may cause an ectopic pregnancy to rupture, resulting in very serious bleeding.
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