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Alias: | Arbolactone | Appearance: | Off-White Crystalline Powder |
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Assay: | 99% | Specific Rotation: | -187.0°~ -193.0° |
Price: | Negotiated | Packing: | Discreet Package |
Mail: | Toni@ycgmp.com | Whatsapp: | +86 18872220653 |
High Light: | raw hormone powders,raw steroid powder |
Arbolactone Female Synthetic Steroids Hormone Inn Usan Drospirenone 67392-87-4
Email:toni@ycgmp.com
Whatsapp +86 18872220653
Drospirenone Specification:
Description | White or almost white power | Almost white power |
Identification | 1. Specific rotation 2. IR |
Conforms Conforms |
Specific rotation | -187.0°~ -193.0° | -192.3° |
Loss on drying | ≤0.5% | 0.23% |
Related Substances | Unspecified impurity <0.10% Total impurities ≤0.3% |
0.09% 0.27% |
Assay(Dry Basis) | 98.0%~102.0% | 99.0% |
Conclusion | Passed |
What is Drospirenone?
Drospirenone (INN, USAN), also known as 1,2-dihydrospirorenone, is a synthetic hormone used in birth control pills and postmenopausal hormone replacement therapy pills.
It is sold under the brand names Yasmin, Yasminelle, Yaz, Beyaz, Ocella, Zarah, Daylette and Angeliq, all of which arecombination products of drospirenone with an estrogen such as ethinylestradiol or estradiol.
Drospirenone differs from other synthetic progestins in that its pharmacological profile in preclinical studies shows it to be closer to the natural progesterone. As such it has potent antimineralocorticoid properties, counteracts the estrogen-stimulated activity of the renin-angiotensin-aldosterone system, and has also been shown to possess mild antiandrogen activity.
The antimineralocorticoid properties exhibited by drospirenone promote sodium excretion and prevent water retention.
Drospirenone Basic Info:
Synonyms: arbolactone
Appearance: Off-White Crystalline Powder
CAS: 67392-87-4
MF: C24H30O3
MW: 366.49
EINECS: 266-679-2
mp: 196-200°C
alpha: -180°(c=0.5, chloroform)
storage temp: -20°C Freezer
Drospirenone Application
1) Drospirenone is an ingredient in some birth control pills and hormone replacement therapy. In combination with ethinyl estradiolit is used as contraception, and for women who want contraception it is also approved by the U. S. Food and Drug Administration(FDA) to treat moderate acne and premenstrual dysphoric disorder.
2) Drospirenone and ethinyl estradiol combination is used to prevent pregnancy. It is a birth control pill that contains two types of hormones, ethinyl estradiol and drospirenone, and when taken properly, prevents pregnancy. It works by stopping a woman's egg from fully developing each month. The egg can no longer accept a sperm and fertilization is prevented.
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