4-AD Raw Estrogen Steroids 4AD Androtex 4-Androstenedione 63-05-8

4-AD Raw Estrogen Steroids 4AD Androtex 4-Androstenedione 63-05-8

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4-Androstenedione COA

What is 4-Androstenedione?

4-Androstenedione is the common precursor of male and female sex hormones. Some 4-Androstenedione is also secreted into the plasma, and may be converted in peripheral tissues to testosterone and estrogens.

4-Androstenedione Application:

1) The primary pathway involves conversion of 17-hydroxypregnenolone to dehydroepiandrosterone by way of 17,20-lyase, with subsequent conversion of dehydroepiandrosterone to 4-Androstenedione via the enzyme 3-β-hydroxysteroid dehydrogenase. The secondary pathway involves conversion of 17-hydroxyprogesterone, most often a precursor to cortisol, to 4-androstenedione directly by way of 17,20-lyase. Thus, 17,20-lyase is required for the synthesis of 4-androstenedione, whether immediately or one step removed.

2) The production of adrenal 4-Androstenedione is governed by ACTH, whereas production of gonadal 4-Androstenedione is under control by gonadotropins. In premenopausal women, the adrenal glands and ovaries each produce about half of the total 4-androstenedione(about 3 mg/day). After menopause, 4-androstenedione production is about halved, due primarily to the reduction of the steroid secreted by the ovary. Nevertheless, 4-androstenedione is the principal steroid produced by the postmenopausal ovary.

4-Androstenedione Basic Info:

Synonyms: 4 - androstenedione; 4 - male (steroid)-ene -3,17 - dione;
CAS No: 63-05-8
Puriy: 99%
Characters: near white crystalline powder, soluble in ethanol, insoluble in water
Molecular Formula: C19H26O2
Molecular Weight: 286.41

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